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Immune response and endocytosis pathways are associated with the resilience against Alzheimer’s disease

29 Sept 2020

Abstract excerpt

Developing Alzheimer's disease (AD) is influenced by multiple genetic variants that are involved in five major AD-pathways. Per individual, these pathways may differentially contribute to the modification of the AD-risk. The pathways involved in the resilience against AD have thus far been poorly addressed. Here, we investigated to what extent each molecular mechanism associates with (i) the increased risk of AD...

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PMID: 32994401
DOI: 10.1038/s41398-020-01018-7

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