Article
Sex-Specific Protective Effects of APOE ε2 on Cognitive Performance.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jan 2021
Lamonja-Vicente Noemí, Dacosta-Aguayo Rosalia, López-Olóriz Jorge, Prades-Senovilla Laia, Roig-Coll Francesca, Castells-Sánchez Alba, Soriano-Raya Juan José, Clemente Inmaculada, Miralbell Júlia, Barrios Maite, López-Cancio Elena, Cáceres Cynthia, Arenillas Juan Francisco, Millán Mónica, Torán Pere, Pera Guillem, Fores Rosa, Alzamora Maria Teresa, Mataró Maria, Via Marc
Abstract excerpt
Apolipoprotein E (APOE) has an important role in the multiple trajectories of cognitive aging. However, environmental variables and other genes mediate the impact of APOE on cognition. Our main objective was to analyze the effect of APOE genotype on cognition and its interactions and relationships with sex, age, lipid profile, C-reactive protein, and Brain-derived neurotrophic factor (BDNF) genotype in a sample...
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