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Article

Arabidopsis small nucleolar RNA monitors the efficient pre-rRNA processing during ribosome biogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 18 Oct 2016

Zhu Pan, Wang Yuqiu, Qin Nanxun, Wang Feng, Wang Jia, Deng Xing Wang, Zhu Danmeng

Abstract excerpt

Ribosome production in eukaryotes requires the complex and precise coordination of several hundred assembly factors, including many small nucleolar RNAs (snoRNAs). However, at present, the distinct role of key snoRNAs in ribosome biogenesis remains poorly understood in higher plants. Here we report that a previously uncharacterized C (RUGAUGA)/D (CUGA) type snoRNA, HIDDEN TREASURE 2 (HID2), acts as an important...

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PMID: 27708161
DOI: 10.1073/pnas.1614852113
PMCID: PMC5081647

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