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Chromosomal copy number based stratification of gastric cancer has added prognostic value to Lauren’s histological classification

19 Aug 2024

Abstract excerpt

BACKGROUND: The Cancer Genome Atlas (TCGA) recognizes four molecular subgroups of gastric cancer: Epstein-Barr virus (EBV) positive, microsatellite instable (MSI), genomically stable (GS), and chromosomal instable (CIN). Since a GS/CIN classifier is lacking, alternative markers such as Lauren's histopathology or CDH1/p53 immunohistochemistry are commonly applied. Here we compared survival of gastric cancer...

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Share to Gastric Cancer Management and Outcomes
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PMID: 39516260
DOI: 10.1038/s44276-024-00078-2

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