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Are Immunohistochemical Markers Useful in Phenotypic Gastric Cancer Classification?

Oncology - 1 Jan 2020

Di Pinto Federica, Armentano Raffaele, Arborea Graziana, Schena Nicolò, Donghia Rossella, Valentini Anna Maria

Abstract excerpt

To identify useful markers for prognostic and therapeutic purposes, The Cancer Genome Atlas (TCGA) provided a molecular classification of gastric cancers (GCs). Previous studies have used immunohistochemistry (IHC) and chromogenic in situ hybridization (CISH) to define immunophenotypic surrogate markers of the molecular alterations. Some critical issues concerning the correct definition of immunophenotypic groups...

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PMID: 32316005
DOI: 10.1159/000506077

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