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Article

Association of variants in PTPN22, CTLA-4, IL2-RA, and INS genes with type 1 diabetes in Emiratis.

Annals of human genetics - 1 Mar 2021

Sharma Charu, R Ali Bassam, Osman Wael, Afandi Bachar, Aburawi Elhadi H, Beshyah Salem A, Al-Mahayri Zeina, Al-Rifai Rami H, Al Yafei Zain, ElGhazali Gehad, Alkaabi Juma

Abstract excerpt

Type 1 diabetes (T1D) is a chronic autoimmune disease with a complex interrelation of genetic and environmental factors. Genetic studies have reported HLA and non-HLA loci as significant contributors to T1D. However, the genetic basis of T1D among Emiratis is unexplored. This study aims to determine the contribution of four genes PTPN22, CTLA-4, IL2-RA, and INS to T1D risk among Emiratis. The association between...

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Share to CTLA-4 Antigen
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Interleukin-2 Receptor alpha Subunit

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

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Identifiers

PMID: 32970831
DOI: 10.1111/ahg.12406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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