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Article

PTPN22 Single-Nucleotide Polymorphisms in Iranian Patients with Type 1 Diabetes Mellitus.

Immunological investigations - 1 May 2017

Abbasi Farzaneh, Soltani Samaneh, Saghazadeh Amene, Soltaninejad Ehsan, Rezaei Arezou, Zare Bidoki Alireza, Bahrami Tayyeb, Amirzargar Ali Akbar, Rezaei Nima

Abstract excerpt

BACKGROUND: PTPN22 plays a crucial role in regulating the function of various cells of the immune system, particularly T cells. Polymorphisms of the PTPN22 gene have been associated with many autoimmune diseases, including type 1 diabetes (T1D) which is a T-cell-mediated disease. OBJECTIVE: The present study was aimed at genotyping of an Iranian population for five polymorphisms of the PTPN22 gene. METHODS: The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

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Source

Identifiers

PMID: 28375784
DOI: 10.1080/08820139.2017.1288239

Genes

PTPN22

Variants

Provenance

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PTPN22 Single-Nucleotide Polymorphisms in Iranian Patients with Type 1 Diabetes Mellitus.PMID 28375784Read ↗

The association of PTPN22 (rs2476601) and IL2RA (rs11594656) polymorphisms with T1D in Egyptian children.Semantic proximity Read ↗

Association of the PTPN22 gene (+1858C/T, -1123G/C) polymorphisms with type 1 diabetes mellitus: a systematic review and meta-analysis.Semantic proximity Read ↗

Genetic Polymorphism of PTPN22 in Autoimmune Diseases: A Comprehensive Review.Semantic proximity Read ↗

Analysis of PTPN22 C1858T gene polymorphism in cases with type 1 diabetes of Azerbaijan, Northwest Iran.Semantic proximity Read ↗

The Potential Role of PTPN-22 C1858T Gene Polymorphism in the Pathogenesis of Type 1 Diabetes in Saudi Population.Semantic proximity Read ↗

PTPN22 gene polymorphism (C1858T) is associated with susceptibility to type 1 diabetes: a meta-analysis of 19,495 cases and 25,341 controls.Semantic proximity Read ↗

A novel single nucleotide polymorphism in the protein tyrosine phosphatase N22 gene (PTPN22) is associated with Type 1 diabetes in a Chinese population.Semantic proximity Read ↗

Genetic Variations of PTPN2 and PTPN22: Role in the Pathogenesis of Type 1 Diabetes and Crohn's Disease.Semantic proximity Read ↗

The association between PTPN22 C1858T gene polymorphism and type 1 diabetes mellitus: an Indonesian study.Semantic proximity Read ↗

The rs1893217 (T/C) polymorphism in PTPN2 gene is not associated with type 1 diabetes mellitus in subjects from Southern Brazil.Semantic proximity Read ↗

Further evidence of a primary, causal association of the PTPN22 620W variant with type 1 diabetes.Semantic proximity Read ↗

Association of PTPN22 Single Nucleotide Polymorphisms with Celiac Disease.Semantic proximity Read ↗

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