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Article

Association of TNF-α, CTLA4, and PTPN22 polymorphisms with type 1 diabetes and other autoimmune diseases in Brazil.

Genetics and molecular research : GMR - 28 Dec 2015

Tavares N A C, Santos M M S, Moura R, Araújo J, Guimarães R L, Crovella S, Brandão L A C

Abstract excerpt

Type 1 diabetes mellitus (T1D) is a complex disorder characterized by an autoimmune response against human pancreatic beta-cells. Patients with T1D can also develop a response toward one or more other factors, such as in autoimmune thyroiditis (AITD) and celiac disease (CD). In the presence of T1D + AITD, the patient is diagnosed with autoimmune polyglandular syndrome type III (APSIII); patients with APSIII may...

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Source

Identifiers

PMID: 26782543
DOI: 10.4238/2015.December.28.42

Genes

TNF
PTPN22
CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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