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Article

The association of PTPN22 (rs2476601) and IL2RA (rs11594656) polymorphisms with T1D in Egyptian children.

Human immunology - 1 Aug 2016

Abdelrahman Hadeel M, Sherief Laila M, Abd Elrahman Doaa M, Alghobashy Ashgan, Elsaadani Hosam F, Mohamed Randa H

Abstract excerpt

BACKGROUND: Type 1 diabetes mellitus (T1D) is a T cell-mediated autoimmune disease characterized by the destruction of pancreatic β cells. PTPN22 and IL2RA polymorphisms have been found to be associated with several autoimmune diseases including T1D. AIMS: We aimed to elucidate the role of PTPN22 and IL2RA polymorphisms in predisposition of T1D in Egyptian children. METHODS: We studied 150 children and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27288719
DOI: 10.1016/j.humimm.2016.06.006

Genes

PTPN22

Variants

rs2476601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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