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Investigating the possible role of toxoplasmosis and Interleukin-1β variants on the immune response in Egyptian diabetic patients.

Microbes and infection - 1 Jan 2025

Ibrahim Asmaa, Kamel Nancy O, Rageh Fatma, Elgamal Rasha, Sakr Mohamed A, Osman Eman M, Ahmed Samar S, Yassin Hend A, Kamel Yasmine N, Othman Reham F, Ramadan Manar Ezzelarab

Abstract excerpt

The study assesses toxoplasmosis seroprevalence in Type 2 Diabetes Mellitus, identifies the potential risk factors, and examines IL-1β expression levels and polymorphisms in those infected with T. gondii. One hundred healthy controls and 200 diabetic patients participated in the study. Diagnosis was made by Immunoassay to measure antibodies of T. gondii, IgM, and IgG, and molecular by targeting the 529 RE gene....

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PMID: 40782940
DOI: 10.1016/j.micinf.2025.105559

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