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Article

Reorganization of the nuclear architecture in the Drosophila melanogaster Lamin B mutant lacking the CaaX box.

Nucleus (Austin, Tex.) - 1 Dec 2020

Bondarenko Semen M, Sharakhov Igor V

Abstract excerpt

Lamins interact with the nuclear membrane and chromatin but the precise players and mechanisms of these interactions are unknown. Here, we tested whether the removal of the CaaX motif from Lamin B disrupts its attachment to the nuclear membrane and affects chromatin distribution. We usedDrosophila melanogaster LamA25 homozygous mutants that lack the CaaX box. We found that the mutant Lamin B was not confined to...

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Identifiers

PMID: 32960740
DOI: 10.1080/19491034.2020.1819704
PMCID: PMC7529411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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