Article

Lamin C regulates genome organization after mitosis

2020-07-28

Abstract excerpt

The dynamic 3D organization of the genome is central to the regulation of gene expression and developmental progression, with its disruption being implicated in various diseases. The nuclear lamina, a proteinaceous meshwork underlying the nuclear envelope (NE), provides both structural and regulatory influences on genome organization through the tethering of large inactive genomic regions, called Lamina Associated...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 55f0ed7b-b8e4-5efe-a868-86f2fc6c8d5a
DOI: 10.1101/2020.07.28.213884

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Lamin C regulates genome organization after mitosisDOI 10.1101/2020.07.28.213884Read

Lamin A/C maintains genome topology and regulates transcriptional programs essential for virus-driven B cell activationSemantic proximity Read

The nuclear lamins: flexibility in function.Semantic proximity Read

Lamin A/C as a Molecular Link Between Nuclear Organization, Chromatin Dynamics, and Tumor ProgressionSemantic proximity Read

Nuclear lamins: key regulators of nuclear structure and activities.Semantic proximity Read

The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse.Semantic proximity Read

Lamins organize the global three-dimensional genome from the nuclear peripherySemantic proximity Read

Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin.Semantic proximity Read

Review: nuclear lamins--structural proteins with fundamental functions.Semantic proximity Read

Lamin A/C safeguards replication initiation by orchestrating chromatin accessibility and PCNA recruitmentSemantic proximity Read

How nuclear envelope dynamics can direct laminopathy phenotypes.Semantic proximity Read

Diverse lamin-dependent mechanisms interact to control chromatin dynamics. Focus on laminopathies.Semantic proximity Read

Depolymerized lamins link nuclear envelope breakdown to mitotic transcriptional quiescenceSemantic proximity Read