Drosophila as a Model for Studying the Roles of Lamins in Normal Tissues and Laminopathies

Abstract excerpt

Nuclear processes are fundamental to the regulation of cellular, tissue, and organismal function, especially in complex multicellular systems. Central to these processes are lamins and lamin-associated proteins, which contribute to nuclear structure, gene expression, and chromatin organization. The discovery that mutations in genes coding for lamins and lamina-associated proteins give rise to rare disorders—collec...

Topics

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• Animals, Genetically Modified
• Cell Nucleus
• Drosophila melanogaster
• Lamin Type A
• Muscles
• Nuclear Envelope
• Tissue Distribution
• Two-Hybrid System Techniques

Identifiers and source

Literature Corpus work

2b2fb7b3-1b9b-54c1-8576-408bd2d3c120

DOI

10.20944/preprints202507.1055.v1