Article
Nestin represents a potential marker of pulmonary vascular remodeling in pulmonary arterial hypertension associated with congenital heart disease.
Journal of molecular and cellular cardiology - 1 Dec 2020
Zhou Jing-Jing, Li Huang, Qian Yu-Ling, Quan Rui-Lin, Chen Xiao-Xi, Li Li, Li Yue, Wang Pei-He, Meng Xian-Min, Jing Xiao-Li, He Jian-Guo
Abstract excerpt
OBJECTIVE: Reportedly, nestin was re-expressed in proliferative synthetic-type pulmonary artery smooth muscle cells (PASMCs) and obligatory for PASMC proliferation in pulmonary arterial hypertension (PAH). Accordingly, nestin is increased in pulmonary vascular lesions of congenital heart disease (CHD)-associated PAH patients. We tested the hypothesis whether nestin was re-expressed in proliferative synthetic-type...
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