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Article

Role of the Stem Cell-Associated Intermediate Filament Nestin in Malignant Proliferation of Non-Small Cell Lung Cancer

3 Feb 2014

Abstract excerpt

BACKGROUND: Nestin is associated with neoplastic transformation, but the mechanisms by which nestin contributes to invasion and malignancy of lung cancer remain unknown. Considering that proliferation is necessary for malignant behavior, we investigated the mechanism of nestin action in association with the proliferative properties of non-small cell lung cancer (NSCLC). METHODS: Nestin expression was examined in...

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PMID: 24498263
DOI: 10.1371/journal.pone.0085584

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