Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nestin expression is upregulated in the fibrotic rat heart and is localized in collagen-expressing mesenchymal cells and interstitial CD31(+)- cells.

PloS one - 1 Jan 2017

Hertig Vanessa, Tardif Kim, Meus Marc Andre, Duquette Natacha, Villeneuve Louis, Toussaint Fanny, Ledoux Jonathan, Calderone Angelino

Abstract excerpt

Renal and lung fibrosis was characterized by the accumulation of collagen-immunoreactive mesenchymal cells expressing the intermediate filament protein nestin. The present study tested the hypothesis that nestin expression was increased in the hypertrophied/fibrotic left ventricle of suprarenal abdominal aorta constricted adult male Sprague-Dawley rats and induced in ventricular fibroblasts by pro-fibrotic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aorta, Abdominal
Share to Hypertrophy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mesoderm

Share to Microvessels

Share to Myocardial Contraction

Share to Nestin

Share to Platelet Endothelial Cell Adhesion Molecule-1

Share to Ventricular Remodeling

Source

Open in PubMed Open full text

Identifiers

PMID: 28448522
DOI: 10.1371/journal.pone.0176147
PMCID: PMC5407835

Genes

SMAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nestin expression is upregulated in the fibrotic rat heart and is localized in collagen-expressing mesenchymal cells and interstitial CD31(+)- cells.PMID 28448522Read ↗

Cardiac resident nestin<sup>+</sup> cells participate in reparative vascularisationSemantic proximity Read ↗

Nestin Expressed by Pre-Existing Cardiomyocytes Recapitulated in Part an Embryonic Phenotype; Suppressive Role of p38 MAPK.Semantic proximity Read ↗

Intermediate filament protein nestin is expressed in developing kidney and heart and might be regulated by the Wilms' tumor suppressor Wt1Semantic proximity Read ↗

Nestin represents a potential marker of pulmonary vascular remodeling in pulmonary arterial hypertension associated with congenital heart disease.Semantic proximity Read ↗

Nestin (+) stem cells independently contribute to neural remodelling of the ischemic heart.Semantic proximity Read ↗

The phenotype and potential origin of nestin+ cardiac myocyte-like cells following infarction.Semantic proximity Read ↗

The neurogenic response of cardiac resident nestin(+) cells was associated with GAP43 upregulation and abrogated in a setting of type I diabetes.Semantic proximity Read ↗

Nestin-Expressing Cells in the Lung: The Bad and the Good PartsSemantic proximity Read ↗

Molecular phenotypes of the human kidney: Myoid stromal cells/telocytes and myoepithelial cells.Semantic proximity Read ↗

Transforming growth factor-beta expression in cardiovascular organs in stroke-prone spontaneously hypertensive rats with the development of hypertension.Semantic proximity Read ↗

Spatiotemporal mapping of matrix remodelling and evidence of in situ elastogenesis in experimental abdominal aortic aneurysms.Semantic proximity Read ↗

The plating of rat scar myofibroblasts on matrigel unmasks a novel phenotype; the self assembly of lumen-like structures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.