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Article

Resident cell lineages are preserved in pulmonary vascular remodeling.

The Journal of pathology - 1 Apr 2018

Crnkovic Slaven, Marsh Leigh M, El Agha Elie, Voswinckel Robert, Ghanim Bahil, Klepetko Walter, Stacher-Priehse Elvira, Olschewski Horst, Bloch Wilhelm, Bellusci Saverio, Olschewski Andrea, Kwapiszewska Grazyna

Abstract excerpt

Pulmonary vascular remodeling is the main pathological hallmark of pulmonary hypertension disease. We undertook a comprehensive and multilevel approach to investigate the origin of smooth muscle actin-expressing cells in remodeled vessels. Transgenic mice that allow for specific, inducible, and permanent labeling of endothelial (Cdh5-tdTomato), smooth muscle (Acta2-, Myh11-tdTomato), pericyte (Cspg4-tdTomato),...

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Source

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Identifiers

PMID: 29359814
DOI: 10.1002/path.5044
PMCID: PMC5903372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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