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Article

TRBV and TRBJ usage, when paired with specific HLA alleles, associates with distinct head and neck cancer survival rates.

Human immunology - 1 Dec 2020

Arndt Mary F, Koohestani Darush M, Chobrutskiy Boris I, Mihyu Moody M, Diaz Michael, Gozlan Etienne C, Yeagley Michelle, Zaman Saif, Roca Andrea M, Blanck George

Abstract excerpt

Common or dominant, T-cell receptor (TCR), V and J usage, in combination with particular human leukocyte antigen (HLA) alleles, has been associated with differing outcomes in viral infections, autoimmunity, and more recently, in cancer. Cervical cancer in particular represents the most dramatic series of distinctions of outcomes associated with differing combinations of dominant V or J usage and HLA alleles,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

Share to Histocompatibility Antigens Class I

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Share to Kaplan-Meier Estimate

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to V(D)J Recombination

Source

Identifiers

PMID: 32950267
DOI: 10.1016/j.humimm.2020.08.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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