Article
Comprehensive analysis of HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 loci and squamous cell cervical cancer risk.
Cancer research - 1 May 2008
Madeleine Margaret M, Johnson Lisa G, Smith Anajane G, Hansen John A, Nisperos Brenda B, Li Sue, Zhao Lue-Ping, Daling Janet R, Schwartz Stephen M, Galloway Denise A
Abstract excerpt
Variation in human major histocompatibility genes may influence the risk of squamous cell cervical cancer (SCC) by altering the efficiency of the T-cell-mediated immune response to human papillomavirus (HPV) antigens. We used high-resolution methods to genotype human leukocyte antigen (HLA) class I (A, B, and Cw) and class II (DRB1 and DQB1) loci in 544 women with SCC and 542 controls. Recognizing that HLA...
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