Article
Novel Common Variants Associated with Obesity and Type 2 Diabetes Detected Using a cFDR Method.
Scientific reports - 27 Nov 2017
Zhang Qiang, Wu Ke-Hao, He Jing-Yang, Zeng Yong, Greenbaum Jonathan, Xia Xin, Liu Hui-Min, Lv Wan-Qiang, Lin Xu, Zhang Wei-Dong, Xi Yuan-Lin, Shi Xue-Zhong, Sun Chang-Qing, Deng Hong-Wen
Abstract excerpt
Genome-wide association studies (GWASs) have been performed extensively in diverse populations to identify single nucleotide polymorphisms (SNPs) associated with complex diseases or traits. However, to date, the SNPs identified fail to explain a large proportion of the variance of the traits/diseases. GWASs on type 2 diabetes (T2D) and obesity are generally focused on individual traits independently, and genetic...
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