Article
Recognition of the organ-specific mutations in metastatic breast cancer by circulating tumor cells isolated in vivo.
Neoplasma - 1 Jan 2021
Li Sainan, Yang Shan, Shi Jiajie, Ding Yawen, Gao Wei, Cheng Meng, Sun Yuqiao, Xie Yanli, Sang Meixiang, Yang Hongxia, Geng Cuizhi
Abstract excerpt
The failure to treat and control the growth of metastases is the main cause of death in breast cancer (BC) patients. Compared to the traditional method of analyzing circulating tumor DNA (ctDNA), capturing intact circulating tumor cells (CTCs) allows us to more accurately characterize mutations and identify suitable targeted therapies. We used CellCollector to collect peripheral CTCs. Thirty metastatic breast...
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