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Article

ddPCR Analysis Reveals BRAF V600E Mutations Are Infrequent in Isolated Pituitary Langerhans Cell Histiocytosis Patients.

Journal of neuropathology and experimental neurology - 4 Dec 2020

Nellan Anandani, Bodlak Avery, Mirsky David M, Mulcahy Levy Jean, Garrington Timothy P, Foreman Nicholas K, Gilani Ahmed, Hayashi Masanori

Abstract excerpt

Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia with a highly variable clinical presentation affecting people of all ages. Mutations in BRAF V600E are the most identifiable molecular alteration in LCH although its incidence in pediatric patients with isolated pituitary stalk involvement is not well described. Pediatric patients with LCH and isolated pituitary stalk involvement typically...

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Identifiers

PMID: 32930721
DOI: 10.1093/jnen/nlaa091
PMCID: PMC8453605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ddPCR Analysis Reveals BRAF V600E Mutations Are Infrequent in Isolated Pituitary Langerhans Cell Histiocytosis Patients.PMID 32930721Read ↗

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