Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinicopathological features and BRAFV600E mutations in patients with isolated hypothalamic-pituitary Langerhans cell histiocytosis.

Diagnostic pathology - 19 Oct 2016

Huo Zhen, Lu Tao, Liang Zhiyong, Ping Fan, Shen Jie, Lu Jingjing, Ma Wenbing, Zhao Dachun, Zhong Dingrong

Abstract excerpt

BACKGROUND: Isolated hypothalamic-pituitary Langerhans cell histiocytosis (HPLCH) is very rare. We investigated the clinicopathological characteristics, endocrine function changes, BRAFV600E mutations and treatments of isolated HPLCH. METHODS: We identified seven patients with isolated HPLCH by reviewing the clinical and pathological files in our hospital from 2007 to 2015. The clinical characteristics of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Genetic Predisposition to Disease

Share to Histiocytosis, Langerhans-Cell

Share to Immunohistochemistry

Share to Mutation

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 27760550
DOI: 10.1186/s13000-016-0548-5
PMCID: PMC5070363

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinicopathological features and BRAFV600E mutations in patients with isolated hypothalamic-pituitary Langerhans cell histiocytosis.PMID 27760550Read ↗

Delayed diagnosis of pituitary LCH with BRAFV600E mutation: A case report and literature review.Semantic proximity Read ↗

Clinical and prognostic features of Langerhans cell histiocytosis in adults.Semantic proximity Read ↗

Langerhans cell histiocytosis in adolescent patients: a single-centre retrospective study.Semantic proximity Read ↗

Clinical features and treatment of Langerhans cell histiocytosis.Semantic proximity Read ↗

Pediatric Langerhans Cell Histiocytosis with BRAF Mutation Affecting Sacral Vertebra: A Case Report and Disease Review.Semantic proximity Read ↗

Erdheim-Chester Disease: A Case Report of BRAF V600E-Negative, MAP2K1-Positive ECD Diagnosed by Blood Next-Generation Sequencing Assay and a Brief Literature Review.Semantic proximity Read ↗

ddPCR Analysis Reveals BRAF V600E Mutations Are Infrequent in Isolated Pituitary Langerhans Cell Histiocytosis Patients.Semantic proximity Read ↗

International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults.Semantic proximity Read ↗

Isolated Langerhans cell histiocytosis of the stomach in adults: An analysis of clinicopathologic characteristics and molecular genetics.Semantic proximity Read ↗

BRAF deletion in adult patients with Langerhans cell histiocytosis correlates with multisystem disease and poor outcomeSemantic proximity Read ↗

BRAF Deletion in Adult Patients with Langerhans Cell Histiocytosis Correlates with Multisystem Disease and Poor Outcomes.Semantic proximity Read ↗

Clinical Study of MAP2K1-Mutated Langerhans Cell Histiocytosis in ChildrenSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.