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Article

Exploring the epigenetic regulation of telomerase reverse transcriptase (TERT) in human cancer cell lines.

Molecular oncology - 1 Oct 2020

McKelvey Brittany A, Zeiger Martha A, Umbricht Christopher B

Abstract excerpt

Telomerase regulation, including TERT promoter methylation, has been of long-standing interest to cancer biologists. Rowland et al. have now vastly expanded their ongoing characterization of TERT promoter methylation in cancer cells, analyzing the methylation patterns of 833 cell lines from 23 human cancers. They document a highly conserved pattern of hypomethylation around the proximal promoter, as well as a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32920953
DOI: 10.1002/1878-0261.12798
PMCID: PMC7530778

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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