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Article

The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study.

PLoS medicine - 1 Sept 2020

Johnson Kelsey E, Siewert Katherine M, Klarin Derek, Damrauer Scott M, Chang Kyong-Mi, Tsao Philip S, Assimes Themistocles L, Maxwell Kara N, Voight Benjamin F

Abstract excerpt

BACKGROUND: A number of epidemiological and genetic studies have attempted to determine whether levels of circulating lipids are associated with risks of various cancers, including breast cancer (BC). However, it remains unclear whether a causal relationship exists between lipids and BC. If alteration of lipid levels also reduced risk of BC, this could present a target for disease prevention. This study aimed to...

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Source

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Identifiers

PMID: 32915777
DOI: 10.1371/journal.pmed.1003302
PMCID: PMC7485834

Genes

ABCA1
ABO
APOC1
APOC2
APOC4
APOE
C2
CETP
MVP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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