Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Mendelian randomization study of the effects of blood lipids on breast cancer risk

21 Sept 2018

Abstract excerpt

Observational studies have reported inconsistent associations between circulating lipids and breast cancer risk. Using results from >400,000 participants in two-sample Mendelian randomization, we show that genetically raised LDL-cholesterol is associated with higher risk of breast cancer (odds ratio, OR, per standard deviation, 1.09, 95% confidence interval, 1.02-1.18, P = 0.020) and estrogen receptor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Cholesterol and Lipid Metabolism
Share to Lipoproteins and Cardiovascular Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30262900
DOI: 10.1038/s41467-018-06467-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Mendelian randomization study of the effects of blood lipids on breast cancer riskPMID 30262900Read ↗

A Mendelian randomization analysis of circulating lipid traits and breast cancer risk.Semantic proximity Read ↗

The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study.Semantic proximity Read ↗

Associations Between Lipid Traits and Breast Cancer Risk: A Mendelian Randomization Study in African WomenSemantic proximity Read ↗

Associations Between Lipid Traits and Breast Cancer Risk: A Mendelian Randomization Study in African WomenSemantic proximity Read ↗

Comprehensive Mendelian randomization analysis of low-density lipoprotein cholesterol and multiple cancersSemantic proximity Read ↗

Comprehensive Mendelian randomization analysis of low-density lipoprotein cholesterol and multiple cancersSemantic proximity Read ↗

Mendelian randomization analyses of 23 known and suspected risk factors and biomarkers for breast cancer overall and by molecular subtypes.Semantic proximity Read ↗

Associations of blood lipids and LDL cholesterol lowering drug-targets with colorectal cancer risk: a Mendelian randomisation study.Semantic proximity Read ↗

Causal association between lipid-lowering drugs and cancers: A drug target Mendelian randomization study.Semantic proximity Read ↗

Joint Genetic Inhibition of PCSK9 and CETP and the Association With Coronary Artery Disease: A Factorial Mendelian Randomization Study.Semantic proximity Read ↗

Mendelian randomization in (epi)genetic epidemiology: an effective tool to be handled with care.Semantic proximity Read ↗

Predicting the effect of statins on cancer risk using genetic variants from a Mendelian randomization study in the UK Biobank.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.