Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive Mendelian randomization analysis of low-density lipoprotein cholesterol and multiple cancers

18 Dec 2024

Abstract excerpt

PURPOSE: The aim of this study was to investigate the causal relationship between low-density lipoprotein cholesterol (LDL-C) and five cancers (breast, cervical, thyroid, prostate and colorectal) using the Mendelian Randomization (MR) method, with a view to revealing the potential role of LDL-C in the development of these cancers. METHODS: We used gene variant data and disease data from the Genome-Wide...

Topics

Join the communities discussing this publication.

Cancer, Lipids, and Metabolism
Genetic Associations and Epidemiology
Lipoproteins and Cardiovascular Health

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39692937
DOI: 10.1007/s12672-024-01684-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive Mendelian randomization analysis of low-density lipoprotein cholesterol and multiple cancersPMID 39692937Read ↗

Comprehensive Mendelian randomization analysis of low-density lipoprotein cholesterol and multiple cancersSemantic proximity Read ↗

Causal association between lipid-lowering drugs and cancers: A drug target Mendelian randomization study.Semantic proximity Read ↗

Causal relationship between lipid-lowering drugs and ovarian cancer, cervical cancer: a drug target mendelian randomization study.Semantic proximity Read ↗

Associations of blood lipids and LDL cholesterol lowering drug-targets with colorectal cancer risk: a Mendelian randomisation study.Semantic proximity Read ↗

Lipids, lipid-modifying drug Target genes and Bladder cancer: a Mendelian randomization studySemantic proximity Read ↗

The Causal Relationship between PCSK9 Inhibitors and Malignant Tumors: A Mendelian Randomization Study Based on Drug TargetingSemantic proximity Read ↗

Blood lipid genetic scores, the HMGCR gene and cancer risk: a Mendelian randomization study.Semantic proximity Read ↗

Blood Lipids and the Risk of Colorectal Cancer: Mendelian Randomization Analyses in the Japanese Consortium of Genetic Epidemiology Studies.Semantic proximity Read ↗

Causal association between remnant cholesterol level and risk of cardiovascular diseases: a bidirectional two sample mendelian randomization study.Semantic proximity Read ↗

Systematic review of Mendelian randomization studies on risk of cancer.Semantic proximity Read ↗

A Mendelian randomization study of the effects of blood lipids on breast cancer riskSemantic proximity Read ↗

Causal relationship between lipid-lowering drugs and ocular disorders: A drug-targeted Mendelian randomization studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.