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Associations Between Lipid Traits and Breast Cancer Risk: A Mendelian Randomization Study in African Women

1 May 2025

Abstract excerpt

BACKGROUND: Blood lipids are implicated in the development of breast cancer (BC), though the genetic connection remains unclear, particularly in African populations. Observational studies on this topic are limited by confounding factors and reverse causation, potentially affecting the reliability of findings. METHODS: We applied univariate and multivariable two-sample Mendelian randomization to assess the causal...

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PMID: 40318100
DOI: 10.1002/cam4.70928

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