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Article

Resistance to paclitaxel induces glycophenotype changes and mesenchymal-to-epithelial transition activation in the human prostate cancer cell line PC-3.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2020

da Fonseca Leonardo Marques, Calvalhan Danilo Macedo, Previato Jose Osvaldo, Mendonça Previato Lucia, Freire-de-Lima Leonardo

Abstract excerpt

The development of the multidrug resistance phenotype is one of the major challenges faced in the treatment of cancer. The multidrug resistance phenotype is characterized by cross-resistance to drugs with different chemical structures and mechanisms of action. In this work, we hypothesized that the acquisition of resistance in cancer is accompanied by activation of the epithelial-to-mesenchymal transition...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32914709
DOI: 10.1177/1010428320957506

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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