Article
Mechanotransduction-Induced Reversible Phenotypic Switching in Prostate Cancer Cells.
Biophysical journal - 28 Mar 2017
Aw Yong Koh Meng, Sun Yubing, Merajver Sofia D, Fu Jianping
Abstract excerpt
Phenotypic plasticity is posed to be a vital trait of cancer cells such as circulating tumor cells, allowing them to undergo reversible or irreversible switching between phenotypic states important for tumorigenesis and metastasis. While irreversible phenotypic switching can be detected by studying the genome, reversible phenotypic switching is often difficult to examine due to its dynamic nature and the lack of...
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