Article
Fluorescent Polysaccharide Nanogels for the Detection of Tumor Heterogeneity in Drug-Surviving Cancer Cells.
Advanced biosystems - 1 Feb 2020
Wang Chenglong, Wang Fanchen, Zhang Jinguo, Liu Lingshan, Xu Guoxiong, Dou Hongjing
Abstract excerpt
Tumor metastasis, recurrence, and drug resistance have been associated with tumor heterogeneity, and thus the identification of tumor heterogeneity has great significance in medicine. The approach provides a way to identify and isolate various cell subtypes from drug-surviving ovarian cancer cells, by synthesizing a series of polysaccharide nanogels and using them in flow cytometry analysis. The results show that...
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