Article
A Mutation in the Carbohydrate Recognition Domain Drives a Phenotypic Switch in the Role of Galectin-7 in Prostate Cancer.
PloS one - 1 Jan 2015
Labrie Marilyne, Vladoiu Maria, Leclerc Bruno G, Grosset Andrée-Anne, Gaboury Louis, Stagg John, St-Pierre Yves
Abstract excerpt
The observation that galectin-7 (gal-7) is specifically expressed in mammary myoepithelial (basal) cells prompted us to investigate whether this protein is expressed in the basal cells of other tissues. Given that breast and prostate cancer have remarkable underlying biological similarities and given the important roles of basal cells in prostate cancer, we examined the expression patterns and role of gal-7 in...
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