Article
Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype.
Oncotarget - 1 Jan 2022
Khosrowabadi Elham, Wenta Tomasz, Keskitalo Salla, Manninen Aki, Kellokumpu Sakari
Abstract excerpt
Several distinct metastasis-associated glycosylation changes have been shown to promote cancer cell invasion and metastasis, the main cause of death of cancer patients. However, it is unclear whether their presence reflects cell- or tissue-specific variations for metastasis, or species needed to drive different phases of the metastatic cascade. To address this issue from a different perspective, we investigated...
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