Article
The influence of DNMT3A and DNMT3B gene polymorphisms on acute myeloid leukemia risk in a Moroccan population.
Current research in translational medicine - 1 Nov 2020
Ait Boujmia Oum Kaltoum, Nadifi Sellama, Dehbi Hind, Lamchahab Mouna, Quessar Asma
Abstract excerpt
Acute myeloid leukemia (AML) is a very complex disease that is linked to environmental, genetic and epigenetic factors. Several Studies have found that aberrations in DNA methylation process play a crucial role in leukemogenesis. The aim of this case control study was to evaluate the association between rs1569686, rs2424913 polymorphisms located in DNMT3B gene and rs7590760 polymorphism located in DNMT3A gene and...
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