Article
Association of Multidrug Resistance Gene-1 (MDR1 C1236T) Polymorphism with the Risk of Acute Myeloid Leukemia in a Moroccan Population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jul 2020
Ait Boujmia Oum Kaltoum, Nadifi Sellama, Dehbi Hind, Lamchahab Mouna, Quessar Asma
Abstract excerpt
The human multidrug resistance MDR1 gene plays a crucial role in the absorption, transport, metabolism and elimination of harmful compounds. An impaired metabolism of these compounds related to genetic polymorphism may cause cancer such as acute myeloid leukemia AML. OBJECTIVE: The present study investigated the relationship between C1236T polymorphism and the risk of AML development in a sample of Moroccan...
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