Article

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture

2020-07-06

Abstract excerpt

The genetic basis of Lewy body dementia (LBD) is not well understood. Here, we performed whole-genome sequencing in large cohorts of LBD cases and neurologically healthy controls to study the genetic architecture of this understudied form of dementia and to generate a resource for the scientific community. Genome-wide association analysis identified five independent risk loci, whereas genome-wide gene-aggregation...

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Literature Corpus work: 66793405-c565-55f8-904b-f985296f8c65
DOI: 10.1101/2020.07.06.185066

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