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Article

Radiation induces dynamic changes to the T cell repertoire in renal cell carcinoma patients

8 Sept 2020

Abstract excerpt

Clinical studies combining radiation and immunotherapy have shown promising response rates, strengthening efforts to sensitize tumors to immune-mediated attack. Thus, there is an ongoing surge in trials using preconditioning regimens with immunotherapy. Yet, due to the scarcity of resected tumors treated in situ with radiotherapy, there has been little investigation of radiation's sole contributions to local and...

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PMID: 32900949
DOI: 10.1073/pnas.2001933117

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