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Article

In vitro reconstitution of autophagic processes.

Biochemical Society transactions - 30 Oct 2020

Alam Jahangir Md, Noda Nobuo N

Abstract excerpt

Autophagy is a lysosomal degradation system that involves de novo autophagosome formation. A lot of factors are involved in autophagosome formation, including dozens of Atg proteins that form supramolecular complexes, membrane structures including vesicles and organelles, and even membraneless organelles. Because these diverse higher-order structural components cooperate to mediate de novo formation of...

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PMID: 32897375
DOI: 10.1042/BST20200130

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