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Autophagy: assays and artifacts

3 Feb 2010

Abstract excerpt

Autophagy is a fundamental and phylogenetically conserved self-degradation process that is characterized by the formation of double-layered vesicles (autophagosomes) around intracellular cargo for delivery to lysosomes and proteolytic degradation. The increasing significance attached to autophagy in development and disease in higher eukaryotes has placed greater importance on the validation of reliable,...

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PMID: 20225337
DOI: 10.1002/path.2694

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