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Article

The Autophagoproteasome a Novel Cell Clearing Organelle in Baseline and Stimulated Conditions

21 Jul 2016

Abstract excerpt

Protein clearing pathways named autophagy (ATG) and ubiquitin proteasome (UP) control homeostasis within eukaryotic cells, while their dysfunction produces neurodegeneration. These pathways are viewed as distinct biochemical cascades occurring within specific cytosolic compartments owing pathway-specific enzymatic activity. Recent data strongly challenged the concept of two morphologically distinct and...

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PMID: 27493626
DOI: 10.3389/fnana.2016.00078

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