Article
Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners.
Autophagy - 1 Jan 2015
Kim Jun Hoe, Hong Seung Beom, Lee Jae Keun, Han Sisu, Roh Kyung-Hye, Lee Kyung-Eun, Kim Yoon Ki, Choi Eui-Ju, Song Hyun Kyu
Abstract excerpt
Autophagy is a bulky catabolic process that responds to nutrient homeostasis and extracellular stress signals and is a conserved mechanism in all eukaryotes. When autophagy is induced, cellular components are sequestered within an autophagosome and finally degraded by subsequent fusion with a lys...
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