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Article

Measurement of Autophagic Activity in Mammalian Cells

1 Mar 2012

Abstract excerpt

Macroautophagy (referred to herein as autophagy) is a process in which cells engulf portions of cytoplasm in double-membrane vesicles called autophagosomes. These autophagosomes can also capture protein oligomers associated with neurodegenerative diseases, infectious agents (like bacteria), and even organelles (like mitochondria). Autophagosomes are transported along microtubules towards the microtubule...

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PMID: 22422474
DOI: 10.1002/0471143030.cb1516s54

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