Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Moderate-Risk Genes for Hereditary Ovarian Cancers Involved in the Homologous Recombination Repair Pathway.

International journal of molecular sciences - 4 Oct 2022

Abe Akiko, Imoto Issei, Ueki Arisa, Nomura Hidetaka, Kanao Hiroyuki

Abstract excerpt

Approximately 20% of cases of epithelial ovarian cancer (EOC) are hereditary, sharing many causative genes with breast cancer. The lower frequency of EOC compared to breast cancer makes it challenging to estimate absolute or relative risk and verify the efficacy of risk-reducing surgery in individuals harboring germline pathogenic variants (GPV) in EOC predisposition genes, particularly those with relatively low...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Carcinoma, Ovarian Epithelial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Homologous Recombination

Share to Ovarian Neoplasms

Share to Recombinational DNA Repair

Source

Open in PubMed Open full text

Identifiers

PMID: 36233090
DOI: 10.3390/ijms231911790
PMCID: PMC9570179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Moderate-Risk Genes for Hereditary Ovarian Cancers Involved in the Homologous Recombination Repair Pathway.PMID 36233090Read ↗

What About the Others? Clinical Management of Gynecologic Cancer Risk in Patients With Moderate-Risk Hereditary Cancer Genes ( ATM , BRIP1 , RAD51C , RAD51D , and PALB2 ).Semantic proximity Read ↗

Rare Germline Genetic Variants and the Risks of Epithelial Ovarian CancerSemantic proximity Read ↗

Genetic Predisposition to Breast and Ovarian Cancers: How Many and Which Genes to Test?Semantic proximity Read ↗

Prevalence and outcomes of germline pathogenic variants of homologous recombination repair genes in ovarian cancer.Semantic proximity Read ↗

Ovarian cancer predisposition beyond BRCA1 and BRCA2 genes.Semantic proximity Read ↗

Homologous Recombination Deficiency: Cancer Predispositions and Treatment Implications.Semantic proximity Read ↗

Functions of Breast Cancer Predisposition Genes: Implications for Clinical Management.Semantic proximity Read ↗

Early-Onset Ovarian Cancer <30 Years: What Do We Know about Its Genetic Predisposition?Semantic proximity Read ↗

Association of Breast and Ovarian Cancers With Predisposition Genes Identified by Large-Scale Sequencing.Semantic proximity Read ↗

Epithelial Ovarian Cancer: Providing Evidence of Predisposition GenesSemantic proximity Read ↗

Epithelial ovarian cancer risk: A review of the current genetic landscapeSemantic proximity Read ↗

Genetic Basis of Breast and Ovarian Cancer: Approaches and Lessons Learnt from Three Decades of Inherited Predisposition TestingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.