Article
In silico analysis predicting effects of deleterious SNPs of human RASSF5 gene on its structure and functions.
Scientific reports - 3 Sept 2020
Hossain Md Shahadat, Roy Arpita Singha, Islam Md Sajedul
Abstract excerpt
Ras association domain-containing protein 5 (RASSF5), one of the prospective biomarkers for tumors, generally plays a crucial role as a tumor suppressor. As deleterious effects can result from functional differences through SNPs, we sought to analyze the most deleterious SNPs of RASSF5 as well as predict the structural changes associated with the mutants that hamper the normal protein-protein interactions. We...
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