Article

<i>In Silico</i> Analysis Predicting Effects of Deleterious SNPs of Human <i>RASSF5</i> Gene on its Structure and Functions

2020-06-05

Abstract excerpt

Ras association domain-containing protein 5 (RASSF5), one of the prospective biomarkers for tumors, generally plays a crucial role as a tumor suppressor. As deleterious effects can result from functional differences through SNPs, we sought to analyze the most deleterious SNPs of RASSF5 as well as predict the structural changes associated with the mutants that hamper the normal protein-protein interactions. We ado...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 36d84237-3b6e-5512-b808-b8320e2fbfe5
DOI: 10.1101/2020.06.05.952952

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>In Silico</i> Analysis Predicting Effects of Deleterious SNPs of Human <i>RASSF5</i> Gene on its Structure and FunctionsDOI 10.1101/2020.06.05.952952Read

In silico analysis predicting effects of deleterious SNPs of human RASSF5 gene on its structure and functions.Semantic proximity Read

Predicting the most deleterious non-synonymous single nucleotide polymorphisms (nsSNPs) of HRAS gene and in silico evaluation of their structural and functional consequences towards diagnosis and prognosis of cancerSemantic proximity Read

Identification of deleterious single nucleotide polymorphism (SNP)s on the human <i>TBX5</i> gene & prediction of their structural & functional consequences: An <i>in silico</i> approachSemantic proximity Read

Approaches and resources for prediction of the effects of non-synonymous single nucleotide polymorphism on protein function and interactions.Semantic proximity Read

Comprehensive Study of Human FBXW7 Deleterious nsSNP's Functional Inference and Susceptibility to Gynaecological CancerSemantic proximity Read

Exploring the structural and functional effect of pRB by significant nsSNP in the coding region of RB1 gene causing retinoblastoma.Semantic proximity Read

Predicting the impact of deleterious single point mutations in SMAD gene family using structural bioinformatics approach.Semantic proximity Read

Applications of computational algorithm tools to identify functional SNPs.Semantic proximity Read

In silico analysis of deleterious SNPs of human MTUS1 gene and their impacts on subsequent protein structure and function.Semantic proximity Read

In‑silico analysis predicting effects of some Protein conding SNPs of human tumor suppressor protein53 (TP53 gene) by using different Bioinformatic toolsSemantic proximity Read

Mutation analysis of pathogenic non-synonymous single nucleotide polymorphisms (nsSNPs) in WFS1 gene through computational approaches.Semantic proximity Read

Prediction of Deleterious Single Nucleotide Polymorphisms in Human p53 GeneSemantic proximity Read