Article
KAT6A amplifications are associated with shorter progression-free survival and overall survival in patients with endometrial serous carcinoma.
PloS one - 1 Jan 2020
Saglam Ozlen, Tang Zhenya, Tang Guilin, Medeiros L Jeffrey, Toruner Gokce A
Abstract excerpt
Somatic copy number alterations (CNA) are common in endometrial serous carcinoma (ESC). We used the Tumor Cancer Genome Atlas Pan Cancer dataset (TCGA Pan Can) to explore the impact of somatic CNA and gene expression levels (mRNA) of cancer-related genes in ESC. Results were correlated with clinico-pathologic parameters such as age of onset, disease stage, progression-free survival (PFS) and overall survival (OS)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
