Article
Novel targeted therapies in uterine serous carcinoma, an aggressive variant of endometrial cancer.
Discovery medicine - 1 Apr 2016
Menderes Gulden, Clark Mitchell, Santin Alessandro D
Abstract excerpt
Uterine serous carcinoma (USC) is a rare but aggressive subtype of endometrial cancer. Although it represents only 10% of all endometrial cancer cases, USC accounts for up to 40% of all endometrial cancer-related recurrences and subsequent deaths. With such a dismal prognosis, there is an expanding role for novel targeted approaches in the treatment of USC. Recent whole-exome sequencing studies have demonstrated...
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