Article
Genomic landscape of endometrial carcinomas of no specific molecular profile.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2022
Momeni-Boroujeni Amir, Nguyen Bastien, Vanderbilt Chad M, Ladanyi Marc, Abu-Rustum Nadeem R, Aghajanian Carol, Ellenson Lora H, Weigelt Britta, Soslow Robert A
Abstract excerpt
Endometrial carcinomas (ECs) classified by The Cancer Genome Atlas (TCGA) as copy number-low (also referred to as "no specific molecular profile" [NSMP]) have a prognosis intermediate between POLE-mutated and copy number-high ECs. NSMP-ECs are a heterogeneous group, however, comprising both relatively indolent and aggressive ECs. We identified a total of 472 NSMP-ECs among 1,239 ECs that underwent clinical...
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