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Article

Genomic Landscape of ctDNA and Real-World Outcomes in Advanced Endometrial Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 16 Dec 2024

Soberanis Pina Pamela, Clemens Keelia, Bubie Adrian, Grant Brooke, Haynes Ginger, Zhang Nicole, Drusbosky Leylah, Lheureux Stephanie

Abstract excerpt

PURPOSE: ctDNA is a novel technique extensively studied in solid tumors, although not currently well defined in endometrial cancer. EXPERIMENTAL DESIGN: A de-identified retrospective analysis of 1,988 patients with advanced/recurrent endometrial cancer was performed. In addition, an analysis of a real-world evidence cohort was completed (n = 1,266). Patients underwent ctDNA testing using Guardant360 during...

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Share to Circulating Tumor DNA
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39417689
DOI: 10.1158/1078-0432.CCR-24-2105
PMCID: PMC11647206

Genes

TP53
PIK3CA
CCNE1
ARID1A
EGFR
KRAS
PTEN

Provenance

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