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Article

TICAM2-related pathway mediates neutrophil exhaustion.

Scientific reports - 1 Sept 2020

Lin RuiCi, Zhang Yao, Pradhan Kisha, Li Liwu

Abstract excerpt

Pathogenic inflammation and immune suppression are the cardinal features that underlie the pathogenesis of severe systemic inflammatory syndrome and sepsis. Neutrophil exhaustion may play a key role during the establishment of pathogenic inflammation and immune suppression through elevated expression of inflammatory adhesion molecules such as ICAM1 and CD11b as well as immune-suppressors such as PD-L1. However,...

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Identifiers

PMID: 32873853
DOI: 10.1038/s41598-020-71379-y
PMCID: PMC7463027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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